Synthetic lethality cancer
「Synthetic lethality cancer」熱門搜尋資訊
「Synthetic lethality cancer」文章包含有：「Definitionofsyntheticlethality」、「Syntheticlethalityandcancer」、「Complexsyntheticlethalityincancer」、「UnleashingthePowerofSyntheticLethality」、「Thepowerandthepromiseofsyntheticlethalityforclinical...」、「NewHorizonsofSyntheticLethalityinCancer」、「SyntheticLethalityinCancerTherapeutics」、「Syntheticlethalityandcancertherapy」、「Syntheticlethality」、「Advancesinsyntheticlethality...
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Definition of synthetic lethality
https://www.cancer.gov
Describes a situation in which mutations (changes) in two genes together result in cell death, but a mutation in either gene alone does not. Cancer cells that only have one mutated gene in a specific pair of genes can depend on the normal partner gene for
Synthetic lethality and cancer
https://www.nature.com
Synthetic lethality is a simple genetic concept that continues to have a major impact on cancer research. Synthetic lethal interaction data from ...
Complex synthetic lethality in cancer
https://www.nature.com
The concept of synthetic lethality has been widely applied to identify therapeutic targets in cancer, with varying degrees of success.
Unleashing the Power of Synthetic Lethality
https://www.ncbi.nlm.nih.gov
Synthetic lethality has emerged as a promising approach to augment the sensitivity of cancer cells to chemotherapy agents. Synthetic lethality ( ...
The power and the promise of synthetic lethality for clinical ...
https://www.sciencedirect.com
Synthetic lethality is a phenomenon wherein the simultaneous deficiency of two or more genes results in cell death, while the deficiency of any individual gene ...
New Horizons of Synthetic Lethality in Cancer
https://pubs.acs.org
This Perspective focuses on the most recent progress in synthetic lethal targets and their inhibitors, within and beyond the DNA damage response ...
Synthetic Lethality in Cancer Therapeutics
https://aacrjournals.org
AbstractSynthetic lethality (SL) provides a conceptual framework for tackling targets that are not classically “druggable,” including loss-of-function.
Synthetic lethality and cancer therapy
https://pubmed.ncbi.nlm.nih.go
We discuss the biological rationale for BRCA-PARP synthetic lethality, how the synthetic lethal approach is being assessed in the clinic, and how mechanisms of ...
Synthetic lethality
https://en.wikipedia.org
Synthetic lethality is defined as a type of genetic interaction where the combination of two genetic events results in cell death or death of an organism.
Advances in synthetic lethality for cancer therapy
https://jhoonline.biomedcentra
Synthetic lethality is a concept in genetics that have a significant impact on cancer study. The concept of synthetic lethality opens a new path ...